Healthy adults harbor more than 1000 species of bacteria that live inside and on the Human body (1). It is considered that 90% of cells in the human body are bacterial, fungal, or otherwise non-human (viruses) (2). The collective genome of these microbes is called microbiome, while the probiome is defined as the autochtonous beneficial bacteria that can be modulated through dietary manipulations.
Microbiome and probiome have attracted particular attention in recent years due to their probable implication in the regulation of a wide variety of physiological functions and potential impact on the risk of diseases. Emerging evidence suggests that dysbiosis (microbial imbalance or maladaptation on or inside the body) affects the maintenance of immune defense, cardiovascular health, glucose metabolism, weight management or digestive health (3) and that microbiota has an implication in the pathogenesis of auto-immune and neurodegenerative diseases (4-5).
Modulating the probiome and consequently the microbiome as well as the metabolome (i.e the metabolites produced in situ) can have positive impacts on the well-being of individuals, at all life stages.
The microbiome can be modulated by :
- Changes in the diet
- Supplementation with probiotics and/or prebiotics
Prebiotics are selectively fermented ingredients that result in specific changes in the composition and/or activity of the gastrointestinal microbiota, thus conferring benefits upon the host health (7).
To propose Ready-to-market ingredients, backed by Science
Olygose was created in 2009. Its ambition is to develop, produce and sell innovative prebiotic ingredients :
- Extracted from plant-based by-products
- Using unique extraction and purification technologies
- Thouroughly backed by science
To develop innovative prebiotics, from plant-based by-products
- Sourcing of sustainable plant-based raw materials
- Unique extraction and purification technologies
- Development of specific analytical methods of caracterisation
- Scientific substantiation & IP protection
- Regulatory clearance for specific markets (foods and beverages, supplements, medical nutrition, infant nutrition)
Process & Nutrition Experts
Olygose is an independent French company which has developed and marketed a range of prebiotics for the food and beverage as well as for the food supplement industries.
A strong team of senior technicians, engineers and doctors is dedicated to the development of new processes and to the substantiation of our ingredient's health benefits.
First Rate R&D; teams
Science and expertise are at the heart of Olygose’s concern, as well as rigor and performance. More than 17 preclinical and clinical studies have been performed so long in order to demonstrate both the safety and the efficacy of our ingredients.
We partner with the best research teams and CROs in order to back our products.