CravingZ’Gone

Satiety boosting ingredient

A healthy microbiota for durable weight management

Overweight and obesity prevalence are a growing concern worldwide and despite many solutions have been proposed to date, few have proven efficient on the long term. While it is now established that increased physical activity and diet re-balancing can dramatically improve weight management in individuals, it is generally difficult for them to sustain what they consider as “efforts” to remain in a healthy weight range.

Managing satiety, through the microbiota modulation, is an innovative way to deal with long-term, healthy weight management.

In the last two decades, evidence about the role of microbiota in the metabolic engineering in general, and more particularly in weight regulation has accumulated, and it is now admitted that the gut microbiota plays a main role.

Key mechanisms linked to the role of microbial metabolites in influencing hormonal profile, inflammation and functioning of the reward centers in the hypothalamus have strengthened the certainty that gut microbiota modulation is probably the next revolution in weight management therapies.

 

 

Benefits

Satietogenic

Clinically-tested satiety-booster (*)

Lactose- and Dairy- free

Suitable for vegan & lactose-intolerant people

Plant-Based

Extracted from legumes

Non GM

Very pure

> 95% GOS, even in powder form

Gently processed

(*) Potential consumer benefits have not been evaluated by EFSA nor FDA and are not to be considered as health claims. They should be considered as potential leads that might be developed into health claims complying with the local legal requirements

 

Mode of action


 

CravingZ’Gone® is very rich in galacto-oligosaccharides (GOS), non-digestible soluble fibers well-known for their prebiotic activity. In contrast with insoluble fibers, commonly used in weight-loss food supplements, Olygose’s GOS do not “fill” the stomach but act on complex metabolic mechanisms by modulating intestinal flora: microbiota stimulates the synthesis of short chain fatty acids (SCFAs), activating a signaling cascade allowing brain control of satiety. This mechanism involves a pool of hormones like ghrelin, leptin, and peptides such as PYY and GLP-1 - cf figure 1

.

Proofs of efficacy

Olygose completed 2 double-blind, vs placebo human studies to evaluate the impact of CravingZ’Gone® supplementation on appetite (2).

In each trial, 4 groups of 22 overweight adults were supplemented with different α-GOS doses or formulations, for 14 days, without following any hypocaloric diet. Appetite scores were then evaluated on a VAS scale during a test-meal. After 14 days:

  • Appetite was decreased
  • Daily caloric intake was also reduced

Results were statistically significant from 6g/day; with an optimum dose, evaluated for a 12g/day supplementation, the product also impacts weight and fat mass.

CravingZ'Gone, by improving satiety, directly promotes reduced food intake and also aid compliance with healthy eating and weight management strategies, by decreasing sensations of hunger

 

Visit our "Experts Corner" to go further!

Applications

Weight Management and satiety boosting

Recommended dosage: 6 to 12g/day

CravingZ’Gone ® is:

  • perfectly soluble in water
  • tasteless and slightly sweet
  • perfectly stable at acid pH as well as to heat treatment

 

This makes our ingredient very easy to formulate, in numerous forms: sticks, instant powder, ready-to-use beverages, nutrition bars, biscuits, etc.

 

Contact us for more information

References

(1) Morel FB & al.α-Galacto-oligosaccharides Dose-dependently Reduce Appetite and Decrease Inflammation in Overweight Adults. J Nutr. 2015 Sep;145(9):2052-9

 

Start a project

We are ready for the challenge
commercial@olygose.com

Find us

Parc Technologique des Rives de l´Oise
60280 Venette - FRANCE

Call us

We are listening to you
+33(0)3 44 90 78 10

© Olygose - Made by 6tematik / AS-im
This website uses some cookies. If you continue navigation, you accept the use of cookies. Warning: blocking cookies prevents the proper operation of the site.